Faculty of Medicine, Dentistry & Health Science Department of Biochemistry and Molecular Biology

Publications 2008

  1. Agüero F, Al-Lazikani B, Aslett M, Berriman M, Buckner FS, Campbell RK, Carmona S, Carruthers IM, Chan AW, Chen F, Crowther GJ, Doyle MA, Hertz-Fowler C, Hopkins AL, McAllister G, Nwaka S, Overington JP, Pain A, Paolini GV, Pieper U, Ralph SA, Riechers A, Roos DS, Sali A, Shanmugam D, Suzuki T, Van Voorhis WC, Verlinde CL. (2008), 'Genomic-scale prioritization of drug targets: the TDR Targets database', Nature Reviews Drug Discovery, 7(11), 900-907.
  2. Ahn S, Byun K, Cho K, Kim JY, Yoo JS, Kim D, Paek SH, Kim SU, Simpson R, Lee B. (2008), Human microglial cells synthesize albumin in brain', PLoS One, 3(7), e2829.
  3. Ahn S, Goode RJA, Simpson R. (2008), 'Stem cell markers: Insights from membrane proteomics?', Proteomics, 8, 4946-4957.
  4. Albiston AL, Morton CJ, Ng HL, Pham V, Yeatman HR, Ye S, Fernando RN, De Bundel D, Ascher DB, Mendelsohn FA, Parker MW, Chai SY. (2008), 'Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase', FASEB Journal, 22(12), 4209-4217.
  5. Alcock FH, Grossmann JG, Gentle IE, Likić VA, Lithgow T, Tokatlidis K. (2008), 'Conserved substrate binding by chaperones in the bacterial periplasm and the mitochondrial intermembrane space', Biochemical Journal, 409(2), 377-387.
  6. Androulakis S, Schmidberger J, Bate MA, DeGori R, Beitz A, Keong C, Cameron B, McGowan S, Porter CJ, Harrison A, Hunter J, Martin JL, Kobe B, Dobson RC, Parker MW, Whisstock JC, Gray J, Treloar A, Groenewegen D, Dickson N, Buckle AM. (2008), 'Federated repositories of X-ray diffraction images', Acta Crystallographica Section D - Biological Crystallography, 64(7), 810-814.
  7. Babon JJ, Sabo JK, Soetopo A, Yao S, Bailey MF, Zhang JG, Nicola NA, Norton RS. (2008), 'The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase', Journal of Molecular Biology, 381(4), 928-940.
  8. Baldwin G, Bailey M, Shehan B, Sims I, Norton R. (2008), 'Tyrosine modification enhances metal ion binding', Biochemical Journal, 416, 77-84.
  9. Bathgate R, Lekgabe ED, McGuane JT, Su Y, Pham T, Ferraro T, Layfield S, Hannan R, Thomas WG, Samuel C, Du XJ. (2008), 'Adenovirus-mediated delivery of relaxin reverses cardiac fibrosis', Molecular and Cellular Endocrinology, 280(1-2), 30-38.
  10. Bellingham S, Coleman L, Masters C, Camakaris J, Hill A. (2008), 'Investigating copper-regulated protein expression in Menkes fibroblasts using antibody microarrays', Proteomics, 8(19), 1819-1839.
  11. Binger KJ, Griffin M, Howlett G. (2008), 'Methionine oxidation inhibits assembly and promotes disassembly of apolipoprotein C-II amyloid fibrils', Biochemistry, 47(38), 10208-10217.
  12. Binger KJ, Pham CL, Wilson LM, Bailey MF, Lawrence LJ, Schuck P, Howlett GJ. (2008), 'Apolipoprotein C-II amyloid fibrils assemble via a reversible pathway that includes fibril breaking and rejoining', Journal of Molecular Biology, 376(4), 1116-1129.
  13. Bogoyevitch M, Arthur PG. (2008), 'Inhibitors of c-Jun N-terminal kinases—JuNK no more?', Biochimica et Biophysica Acta-Proteins and Proteomics, 1784(1), 76-93.
  14. Bojarova P, Denehy EL, Walker I, Loft KJ, De Souza DP, Woo LW, Potter VL, McConville M, Williams S. (2008), 'Direct evidence for ArO-S bond cleavage upon inactivation of Pseudomonas aeruginosa arylsulfatase by aryl sulfamates', Chembiochem, 9(4), 613-623.
  15. Boughton BA, Dobson R, Gerrard A, Hutton C. (2008), 'Conformationally constrained diketopimelic acid analogues as inhibitors of dihydrodipicolinate synthase', Bioorganic and Medicinal Chemistry Letters, 18, 460-463.
  16. Boughton BA, Griffin M, O'Donnell P, Dobson R, Perugini M, Gerrard A, Hutton C. (2008), 'Irreversible inhibition of dihydrodipicolinate synthase by 4-oxo-heptenedioic acid analogues', Bioorganic & Medicinal Chemistry, 16, 9975-9983.
  17. Bremond A, Meynet O, Mahiddine K, Coito S, Tichet M, Scotlandi K, Breittmayer JP, Gounon P, Gleeson P, Bernard A, Bernard G. (2008), 'Regulation of HLA class I surface expression requires CD99 and p230/golgin-245 interaction', Blood, 113(2), 347-357.
  18. Burgess BR, Dobson R, Bailey M, Atkinson SC, Griffin M, Jameson GB, Parker M, Gerrard JA, Perugini M. (2008), 'Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen', Journal of Biological Chemistry. 283(41), 27598-27603.
  19. Butler NS, Theodossis A, Webb AI, Dunstone MA, Nastovska R, Ramarathinam SH, Rossjohn J, Purcell AW, Perlman S. (2008), 'Structural and biological basis of CTL escape in coronavirus-infected mice', Journal of Immunology, 180(6), 3926-3937.
  20. Butler NS, Theodossis A, Webb AI, Nastovska R, Ramarathinam SH, Dunstone MA, Rossjohn J, Purcell AW, Perlman S. (2008), 'Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant', PLoS Pathogens, 4(10), e1000186.
  21. Chai SY, Yeatman HR, Parker MW, Ascher DB, Thompson PE, Mulvey HT, Albiston AL. (2008), 'Development of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase', BMC Neuroscience, 9(2) S14.
  22. Chan L, Kim S, Kwok B, Hill A, Cappai R, Rye K, Garner B. (2008), 'ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein in vitro', Journal of Neurochemistry, 106(2), 793-804.
  23. Chessman D, Kostenko L, Lethborg T, Purcell A, Williamson N, Kjer-Nielsen L, Mifsud N, Tait BD, Holdsworth R, Almeida CA, Nolan D, MacDonald WA, Archbold JK, Kellerher AD, Marriott D, Mallal S, Bharadwaj M, Rossjohn J, McCluskey J. (2008), 'Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity', Immunity, 28, 822-832.
  24. Christiansen D, Milland J, Mouhtouris E, Vaughan H, Pellicci D, McConville M, Godfrey D, Sandrin M. (2008), 'Humans Lack iGb3 due to the absence of functional iGb3-synthase: implications for NKT cell development and transplantation', PLoS Biology, 6(7), 1527-1538.
  25. Clements A, Gaboriaud F, Duval JFL, Gabbe J, Jenney A, Lithgow T, Wijburg O, Hartland E, Strugnell R. (2008), 'The major surface-associated saccharides of Klebsiella pneumoniae contribute to host cell association', PLoS One, 3(11), 1-10.
  26. Courageot MP, Daude N, Nonno R, Paquet S, Di Bari MA, Le Dur A, Chapuis J, Hill AF, Agrimi U, Laude H, Vilette D. (2008), 'A cell line infectible by prion strains from different species', Journal of General Virology, 89(1), 341-347.
  27. Crellin PK, Kovacevic S, Martin KL, Brammananth R, Morita YS, Billman-Jacobe H, McConville MJ, Coppel RL. (2008), 'Mutations in pimE restore lipoarabinomannan synthesis and growth in a Mycobacterium smegmatis lpqW mutant', Journal of Bacteriology, 190(10), 3690-3699.
  28. D'Auvergne J, Gooley P. (2008), 'Optimisation of NMR dynamic models I. Minimisation algorithms and their performance within the model-free and Brownian rotational diffusion spaces', Journal of Biomolecular NMR, 40(2), 107-119.
  29. D'Auvergne J, Gooley P. (2008), 'Optimisation of NMR dynamic models II. A new methodology for the dual optimisation of the model-free parameters and the Brownian rotational diffusion tensor', Journal of Biomolecular NMR, 40(2), 121-133.
  30. Dobson R, Atkinson S, Perugini M. (2008), 'The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum', Acta Crystallographica Section F - Structural Biology and Crystallization Communications, 64(3), 206-208.
  31. Dobson R, Dogovski C, Perugini M. (2008), 'Purification, crystallization and preliminary X-ray diffraction studies to near-atomic resolution of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus', Acta Crystallographica Section F - Structural Biology and Crystallization Communications, 64(7), 659-661.
  32. Dobson R, Griffin M, Devenish SRA, Pearce FG, Hutton C, Gerrard JA, Jameson GB, Perugini M. (2008), 'Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase', Protein Science, 17(12), 2080-2090.
  33. Donnelly P, Caragounis A, Du T, Laughton K, Volitakis I, Cherny R, Sharples R, Hill A, Li Q, White A, Barnham K, Masters C. (2008), 'Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide', Journal of Biological Chemistry, 283(8), 4568-4577.
  34. Fry B, Scheib H, Van Der Weerd L, Young B, McNaughtan J, Ramjan SF, Vidal N, Poelmann RE, Norman JA. (2008), 'Evolution of an arsenal: structural and functional diversification of the venom system in the advanced snakes (Caenophidia)', Molecular and Cellular Proteomics, 7(2), 215-246.
  35. Gatsos X, Perry A, Anwari K, Dolezal P, Wolynec P, Likic V, Purcell A, Buchanan K, Lithgow T. (2008), 'Protein secretion and outer membrane assembly in Alphaproteobacteria', FEMS Microbiology Reviews, 32(6), 995-1009.
  36. Georgakopoulos T, Moss S, Kanagasundaram V. (2008), 'Integrin CD11c contributes to monocyte adhesion with CD11b in a differential manner and requires Src family kinase activity', Molecular Immunology, 45(13), 3671-3681.
  37. Georgiou HM, Lappas M, Georgiou GM, Marita A, Bryant VJ, Hiscock R, Permezel M, Khalil Z, Rice GE. (2008), 'Screening for biomarkers predictive of gestational diabetes mellitus', Acta Diabetologica, 45, 157-165.
  38. Gliddon B, Nguyen N, Gunn PA, Gleeson P, Van Driel I. (2008), 'Isolation, culture and adenoviral transduction of parietal cells from mouse gastric mucosa', Biomedical Materials, 3(3), 034117.
  39. Greening DW, Glenister KM, Kapp EA, Moritz RL, Sparrow RL, Lynch GW, Simpson RJ. (2008), 'Comparison of human platelet membrane-cytoskeletal proteins with the plasma proteome: Towards understanding the platelet-plasma nexus', Proteomics - Clinical Applications, 2(1), 63-77.
  40. Griffin M, Dobson R, Pearce FG, Antonio L, Whitten AE, Liew CK, Mackay JP, Trewhella J, Jameson GB, Perugini M, Gerrard JA. (2008), 'Evolution of quaternary structure in a homotetrameric enzyme', Journal of Molecular Biology, 380(4), 691-703.
  41. Griffin M, Mok LYM, Fitzpatrick L, Pham C, Waddington LJ, Perugini M, Howlett G. (2008), 'Phospholipid interaction induces molecular-level polymorphism in apolipoprotein C-II amyloid fibrils via alternative assembly pathways', Journal of Molecular Biology, 375(1), 240-256.
  42. Grounds M, Radley HG, Gebski BL, Bogoyevitch M, Shavlakadze T. (2008), 'Implications of cross-talk between tumour necrosis factor and insulin-like growth factor-1 signalling in skeletal muscle', Clinical and Experimental Pharmacology and Physiology, 35(7), 846-851.
  43. Gunawardana D, Cheng H, Gayler K. (2008), 'Identification of functional domains in Arabidopsis thaliana mRNA decapping enzyme (AtDcp2)', Nucleic Acids Research, 36(1), 203-216.
  44. Hansen G, Hercus TR, McClure BJ, Stomski FC, Dottore M, Powell J, Ramshaw H, Woodcock JM, Xu Y, Guthridge M, McKinstry WJ, Lopez AF, Parker MW. (2008), 'The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation', Cell, 134(3), 496-507.
  45. Hatters D. (2008), 'Protein misfolding inside cells: the case of huntingtin and Huntington's disease', IUBMB Life, 60(11), 724-728.
  46. Hogan TV, Ang KY, Gleeson P, Van Driel I. (2008), 'Extrathymic mechanisms of T cell tolerance: lessons from autoimmune gastritis', Journal of Autoimmunity, 31(3), 268-273.
  47. Akhter Hossain M, Bathgate RA, Kong CK, Shabanpoor F, Zhang S, Haugaard-Jönsson LM, Rosengren KJ, Tregear GW, Wade JD. (2008), 'Synthesis, conformation, and activity of human insulin-like peptide 5 (INSL5)', Chembiochem, 9(11), 1816-1822.
  48. Hossain MA, Rosengren KJ, Haugaard-Jönsson LM, Zhang S, Layfield S, Ferraro T, Daly NL, Tregear GW, Wade JD, Bathgate RA. (2008), 'The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors', Journal of Biological Chemistry, 283(25), 17287-17297.
  49. Hulett JM, Lueder FB, Chan NCK, Perry A, Wolynec P, Likic V, Gooley P, Lithgow T. (2008), 'The transmembrane segment of Tom20 is recognised by Mim1 for docking to the mitochondrial TOM complex', Journal of Molecular Biology, 376(3), 694-704.
  50. Hung A, Griffin MD, Howlett GJ, Yarovsky I. (2008), 'Effects of oxidation, pH and lipids on amyloidogenic peptide structure: implications for fibril formation', European Biophysics Journal, 38(1), 99-110.
  51. Ignjatovic V, Summerhayes R, Yip YY, Monagle P. (2008), 'The in vitro anticoagulant effects of Danaparoid, Fondaparinux, and Lepirudin in children compared to adults', Thrombosis Research, 122(5), 709-714.
  52. Iseli TJ, Oakhill JS, Bailey MF, Wee S, Walter M, van Denderen BJ, Castelli LA, Katsis F, Witters LA, Stapleton D, Macaulay SL, Michell BJ, Kemp BE. (2008), 'AMP-activated protein kinase subunit interactions: beta1:gamma1 association requires beta1 Thr-263 and Tyr-267', Journal of Biological Chemistry, 283(8), 4799-4807.
  53. James PF, Perugini M, O'Hair R. (2008), 'Electron capture dissociation of complexes of diacylglycerophosphocholine and divalent metal ions: competition between charge reduction and radical induced phospholipid fragmentation', Journal of the American Society for Mass Spectrometry, 19, 978-986.
  54. Ji H, Erfani N, Tauro BJ, Kapp EA, Zhu H, Moritz RL, Lim JWE, Simpson R. (2008), 'Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-driven exosomes', Electrophoresis, 29(12), 2660-2671.
  55. Kedzierska K, Guillonneau C, Gras S, Hatton L, Webby R, Purcell A, Rossjohn J, Doherty P, Turner S. (2008), 'Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy', Proceedings of the National Academy of Sciences, USA, 105(49), 19408-19413.
  56. Kefala G, Evans GL, Griffin MD, Devenish SR, Pearce FG, Perugini MA, Gerrard JA, Weiss MS, Dobson RC. (2008), 'Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis', Biochemical Journal, 411(2), 351-360.
  57. Kotsonis SE, Powell IB, Pillidge CJ, Limsowtin GK, Hillier AJ, Davidson BE. (2008), 'Characterization and genomic analysis of phage asccphi28, a phage of the family Podoviridae infecting Lactococcus lactis. Applied and Environmental Microbiology, 74(11), 3453-3460.
  58. Kulkarni K, Zhao A, Purcell A, Perlmutter P. (2008), ,The enantioselective total synthesis and unambiguous proof of the absolute stereochemistry of pervilleine C', Synlett, 14, 2209-2212.
  59. Kvansakul M, Yang H, Fairlie WD, Czabotar PE, Fischer SF, Perugini MA, Huang DC, Colman PM. (2008), 'Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands', Cell Death & Differentiation, 15(10), 1564-1571.
  60. La Gruta N, Thomas P, Webb A, Dunstone M, Cukalac T, Doherty P, Purcell A, Rossjohn J, Turner S. (2008), 'Epitope-specific TCRß repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides', Proceedings of the National Academy of Sciences, USA, 105(6), 2034-2039.
  61. Lam AKY, Ramarathinam S, Purcell A, O'Hair R. (2008), 'Can alpha- and beta-alanine containing peptides be distinguished based on the CID spectra of their protonated ions?', Journal of the American Society for Mass Spectrometry, 19(12), 1743-1754.
  62. Lamontagne A, Hunter C, Vallance D, Holloway A. (2008), Asbestos disease in Australia: Looking forward and looking back. New Solutions, 18(3), 361-373.
  63. Lawson V, Vella L, Stewart J, Sharples R, Klemm H, Machalek D, Masters C, Cappai R, Collins S, Hill A. (2008), 'Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture', International Journal of Biochemistry and Cell Biology, 40(12), 2793-2801.
  64. Lea-Smith DJ, Martin KL, Pyke JS, Tull D, McConville MJ, Coppel RL, Crellin PK. (2008), 'Analysis of a new mannosyltransferase required for the synthesis of phosphatidylinositol mannosides and lipoarbinomannan reveals two lipomannan pools in corynebacterineae', Journal of Biological Chemistry, 283(11), 6773-6782.
  65. Lees EE, Gunzburg MJ, Nguyen TL, Howlett GJ, Rothacker J, Nice EC, Clayton AH, Mulvaney P. (2008), 'Experimental determination of quantum dot size distributions, ligand packing densities, and bioconjugation using analytical ultracentrifugation', Nano Letters, 8(9), 2883-2890.
  66. Lieu Z, Lock J, Hammond L, La Gruta N, Stow J, Gleeson P. (2008), 'A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo', Proceedings of the National Academy of Sciences, USA, 105(9), 3351-3356.
  67. Lim JP, Wang JT, Kerr MC, Teasdale RD, Gleeson PA. (2008), 'A role for SNX5 in the regulation of macropinocytosis', BMC Cell Biology, 9, 58.
  68. Lithgow T, Chan NCK. (2008), 'The peripheral membrane subunits of the SAM complex function codependently in mitochondrial outer membrane biogenesis', Molecular Biology of the Cell, 19(1), 126-136.
  69. Mifsud N, Purcell A, Chen W, Holdsworth R, Tait BD, McCluskey J. (2008), 'Immunodominance hierarchies and gender bias in direct T CD8-cell alloreactivity', American Journal of Transplantation, 8, 121-132.
  70. Miles AJ, Drechsler A, Kristan K, Anderluh G, Norton RS, Wallace BA, Separovic F. (2008), 'The effects of lipids on the structure of the eukaryotic cytolysin equinatoxin II: a synchrotron radiation circular dichroism spectroscopic study', Biochimica et Biophysica Acta-Biomembranes, 1778(10), 2091-2096.
  71. Mills R, Sim C, Mok , Mulhern T, Culvenor J, Cheng H. (2008), 'Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)', Journal of Neurochemistry, 105, 18-33.
  72. Mitsakos V, Dobson R, Pearce G, Devenish R, Evans L, Burgess BR, Perugini M, Gerrard A, Hutton C. (2008), 'Inhibiting dihydrodipicolinate synthase across species: Towards specificity for pathogens?', Bioorganic and Medicinal Chemistry Letters, 18, 842-844.
  73. Naderer T, McConville M. (2008), 'The Leishmania-macrophage interaction: a metabolic perspective', Cellular Microbiology, 10(2), 301-308.
  74. Naderer T, Wee Pei Yi E, McConville M. (2008), 'Role of hexosamine biosynthesis in Leishmania growth and virulence', Molecular Microbiology, 69(4), 858-869.
  75. Naylor R, Hill A, Barnham K. (2008), 'Neurotoxicity in Alzheimer's disease: is covalently crosslinked A beta responsible', European Biophysics Journal with Biophysics Letters, 37(3), 265-268.
  76. Naylor RJ, Hill A, Barnham K. (2008), 'Is covalently crosslinked Abeta responsible for synaptotoxicity in Alzheimer's disease', Current Alzheimer Research, 5(6), 533-539.
  77. Ng D, Gebski L, Grounds D, Bogoyevitch M. (2008), 'Myoseverin disrupts sarcomeric organization in myocytes: An effect independent of microtubule assembly inhibition', Cell Motility and the Cytoskeleton, 65(1), 40-58.
  78. Nguyen TH, Mifsud NA, Stewart LA, Rose MJ, Etto TL, Williamson NA, Purcell AW, Kotsimbos T, Schwarer AP. (2008), 'Refinement in the production and purification of recombinant HCMV IE1-pp65 protein for the generation of epitope-specific T cell immunity', Protein Expression and Purification, 61(1), 22-30.
  79. Parker B, Ciocca DR, Bidwell B, Gago FE, Fanelli MA, George J, Slavin J, Moller A, Steel R, Pouliot N, Eckhardt B, Henderson M, Anderson R. (2008), 'Primary tumour expression of the cysteine cathepsin inhibitor Stevin A inhibits distant metastasis in breast', Journal of Pathology, 214(3), 337-346.
  80. Parker LJ, Ciccone S, Italiano LC, Primavera A, Oakley AJ, Morton CJ, Hancock NC, Bello ML, Parker MW. (2008), 'The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants', Journal of Molecular Biology, 380(1), 131-144.
  81. Pearce FG, Dobson R, Weber A, Lane LA, McCammon MG, Squire MA, Perugini M, Jameson GB, Robinson CV, Gerrard JA. (2008), 'Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme', Biochemistry, 47, 12108-12117.
  82. Pearce MC, Morton CJ, Feil SC, Hansen G, Adams JJ, Parker MW, Bottomley SP. (2008), 'Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding', Protein Science, 17(12), 2127-2133.
  83. Perry A, Rimmer KA, Mertens H, Waller R, Mulhern T, Lithgow T, Gooley P. (2008), 'Structure, topology and function of the translocase of the outer membrane of mitochondria', Plant Physiology and Biochemistry, 46(3), 265-274.
  84. Perugini M. (2008), 'Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: towards a monomeric enzyme', Biochemistry, 47, 12108-12117.
  85. Price KA, Filiz G, Caragounis A, Du T, Laughton K, Masters C, Sharples R, Hill A, Li Q, Donnelly P, Barnham K, Crouch P, White A. (2008), 'Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide', International Journal of Biochemistry and Cell Biology, 40(9), 1901-1917.
  86. Purcell A, Elliot T. (2008), 'Molecular machinations of the MHC-I peptide loading complex', Current Opinion in Immunology, 20(1), 75-81.
  87. Purcell A, Van Driel I, Gleeson P. (2008), 'Impact of glycans on T-cell tolerance to glycosylated self-antigens', Immunology and Cell Biology, 86(7), 574-579.
  88. Qiu W, Hu M, Sridhar A, Opeskin K, Fox S, Shipitsin M, Trivett M, Thompson ER, Ramakrishna M, Gorringe KL, Polyak K, Haviv I, Campbell IG. (2008), 'No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas', Nature Genetics, 40(5), 650-655.
  89. Qu Y, Egelund J, Gilson PR, Houghton F, Gleeson PA, Schultz CJ, Bacic A. (2008), 'Identification of a novel group of putative Arabidopsis thaliana beta-(1,3)-galactosyltransferases', Plant Molecular Biology, 68(1-2), 43-59.
  90. Rasheed W, Bishton M, Johnstone RW, Prince HM. (2008), 'Histone deacetylase inhibitors in lymphoma and solid malignancies', Expert Review of Anticancer Therapy, 8(3), 413-432.
  91. Ryan TM, Howlett G, Bailey M. (2008), 'Fluorescence detection of a lipid-induced tetrameric intermediate in amyloid fibril formation by apolipoprotein C-II', Journal of Biological Chemistry, 283(50), 35118-35128.
  92. Samuel C, Hewitson T, Zhang Y, Kelly D. (2008), 'Relaxin ameliorates fibrosis in experimental diabetic cardiomyopathy', Endocrinology, 149(7), 3286-3293.
  93. Sanij E, Hannan R. (2008), 'Chromatin organization and expression', Genome Biology, 9(4), 305.
  94. Saunus JM, French JD, Edwards S, Beveridge DJ, Hatchell EC, Wagner SA, Stein SR, Davidson A, Simpson K, Francis GD, Leedman PJ, Brown M. (2008), 'Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 by the RNA binding protein HuR', Cancer Research, 68(22), 9469-9478.
  95. Schneider A, Bursac D, Lithgow T. (2008), 'The direct route: a simplified pathway for protein import into the mitochondrion of trypanosomes', Trends in Cell Biology, 18(1), 12-18.
    96. Scott W, Van Denderen B, Jorgensen B, Honeyman JE, Steinberg G, Oakhill S, Iseli TJ, Koay A, Gooley P,
  96. Kemp B, Stapleton D. (2008), 'Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes', Chemistry & Biology, 15(11), 1220-1230.
  97. Shabanpoor F, Hughes RA, Bathgate RA, Zhang S, Scanlon DB, Lin F, Hossain MA, Separovic F, Wade JD. (2008), 'Solid-phase synthesis of europium-labeled human INSL3 as a novel probe for the study of ligand-receptor interactions', Bioconjugate Chemistry, 19, 1456-1463.
  98. Sharples R, Vella L, Nisbet R, Naylor R, Perez K, Barnham K, Masters C, Hill A. (2008), 'Inhibition of γ-secretase causes increased secretion of amyloid precursor C-terminal fragments in association with exosomes', FASEB Journal, 22(5), 1469-1478.
  99. Simpson R, Bernhard O, Greening DW, Moritz RL. (2008), 'Proteomics-driven cancer biomarker discovery: looking to the future', Current Opinion in Chemical Biology, 12, 72-77.
  100. Sprung CN, Davey DS, Withana NP, Distel LV, McKay MJ. (2008), 'Telomere length in lymphoblast cell lines derived from clinically radiosensitive cancer patients', Cancer Biology & Therapy, 7(5), 638-644.
  101. Tilley L, Sougrat R, Lithgow T, Hanssen E. (2008), 'The twists and turns of Maurer's cleft trafficking in P. falciparum-infected erythrocytes', Traffic, 9(2), 187-197.
  102. Tothill RW, Tinker AV, George J, Brown R, Fox SB, Lade S, Johnson DS, Trivett MK, Etemadmoghadam D, Locandro B, Traficante N, Fereday S, Hung JA, Chiew YE, Haviv I; Australian Ovarian Cancer Study Group, Gertig D, DeFazio A, Bowtell DD. (2008), 'Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome', Clinical Cancer Research, 14(16), 5198-5208.
  103. Tsoutsman T, Kelly M, Ng D, Tan J, Tu E, Lam L, Bogoyevitch M, Seidman CE, Semsarian C. (2008), 'Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy', Circulation, 117(14), 1820-1831.
  104. van der Westhuizen ET, Halls ML, Samuel CS, Bathgate RA, Unemori EN, Sutton SW, Summers RJ. (2008), 'Relaxin family peptide receptors – from orphans to therapeutic targets', Drug Discovery Today, 13(15-16), 640-651.
  105. Van Driel I, Ang KY. (2008), 'Role of regulatory T cells in gastrointestinal inflammatory disease', Journal of Gastroenterology & Hepatology, 23(2), 171-7.
  106. Vella L, Greenwood D, Cappai R, Scheerlinck J, Hill A. (2008), 'Enrichment of prion protein in exosomes derived from ovine cerebral spinal fluid', Veterinary Immunology and Immunopathology, 124(3-4), 385-393.
  107. Vella L, Sharples R, Nisbet RM, Cappai R, Hill A. (2008), 'The role of exosomes in the processing of proteins associated with neurodegenerative diseases', European Biophysics Journal with Biophysics Letters, 37(3), 323-332.
  108. Vince JE, Tull D, Spurck T, Derby MC, McFadden G, Gleeson P, Gokool S, McConville M. (2008), 'Leishmania adaptor protein-1 subunits are required for normal lysosome traffic, flagellum biogenesis, lipid homeostasis, and adaptation to temperatures encountered in the Mammalian host', Eukaryotic Cell, 7(8), 1256-1267.
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Publications - 2004, Publications - 2005, Publications - 2006, Publications - 2007

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